Sonochemical Synthesis of 2'-Hydroxy-Chalcone Derivatives with Potential Anti-Oomycete Activity.
Identifieur interne : 000052 ( Main/Exploration ); précédent : 000051; suivant : 000053Sonochemical Synthesis of 2'-Hydroxy-Chalcone Derivatives with Potential Anti-Oomycete Activity.
Auteurs : Génesis L Pez [Chili] ; Marco Mellado [Chili] ; Enrique Werner [Chili] ; Bastián Said [Chili] ; Patricio Godoy [Chili] ; Nelson Caro [Chili] ; Ximena Besoain [Chili] ; Iván Montenegro [Chili] ; Alejandro Madrid [Chili]Source :
- Antibiotics (Basel, Switzerland) [ 2079-6382 ] ; 2020.
Abstract
This work reports on the synthesis of eight new 2'-hydroxy-chalcones with potential anti-phytopathogenic applications in agroindustry, among others, via Claisen-Schmidt condensation and ultrasound assisted reaction. Assays showed three chalcones with allyl moieties strongly inhibited growth of phytopathogenic oomycete Phytophthora infestans; moreover, compound 8a had a half maximal effective concentration (EC50) value (32.5 µg/mL) similar to that of metalaxyl (28.6 µg/mL). A software-aided quantitative structure-activity relationship (QSAR) analysis of the whole series suggests that the structural features of these new chalcones-namely, the fluoride, hydroxyl, and amine groups over the carbon 3' of the chalcone skeleton-increase anti-oomycete activity.
DOI: 10.3390/antibiotics9090576
PubMed: 32899705
PubMed Central: PMC7560025
Affiliations:
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Leopoldo Carvallo 270, Playa Ancha, Valparaíso 2340000, Chile.</nlm:affiliation><country xml:lang="fr">Chili</country><wicri:regionArea>Laboratorio de Productos Naturales y Síntesis Orgánica (LPNSO), Departamento de Química, Facultad de Ciencias Naturales y Exactas, Universidad de Playa Ancha, Avda. Leopoldo Carvallo 270, Playa Ancha, Valparaíso 2340000</wicri:regionArea><wicri:noRegion>Valparaíso 2340000</wicri:noRegion></affiliation></author><author><name sortKey="Mellado, Marco" sort="Mellado, Marco" uniqKey="Mellado M" first="Marco" last="Mellado">Marco Mellado</name><affiliation wicri:level="1"><nlm:affiliation>Instituto de Química, Facultad de Ciencias, Pontificia Universidad Católica de Valparaíso, Av. Universidad #330, Curauma, Valparaíso 2340000, Chile.</nlm:affiliation><country xml:lang="fr">Chili</country><wicri:regionArea>Instituto de Química, Facultad de Ciencias, Pontificia Universidad Católica de Valparaíso, Av. Universidad #330, Curauma, Valparaíso 2340000</wicri:regionArea><wicri:noRegion>Valparaíso 2340000</wicri:noRegion></affiliation></author><author><name sortKey="Werner, Enrique" sort="Werner, Enrique" uniqKey="Werner E" first="Enrique" last="Werner">Enrique Werner</name><affiliation wicri:level="1"><nlm:affiliation>Departamento de Ciencias Básicas, Campus Fernando May Universidad del Biobío. Avda. Andrés Bello 720, Casilla 447, Chillán 3780000, Chile.</nlm:affiliation><country xml:lang="fr">Chili</country><wicri:regionArea>Departamento de Ciencias Básicas, Campus Fernando May Universidad del Biobío. Avda. Andrés Bello 720, Casilla 447, Chillán 3780000</wicri:regionArea><wicri:noRegion>Chillán 3780000</wicri:noRegion></affiliation></author><author><name sortKey="Said, Bastian" sort="Said, Bastian" uniqKey="Said B" first="Bastián" last="Said">Bastián Said</name><affiliation wicri:level="1"><nlm:affiliation>Departamento de Química, Universidad Técnica Federico Santa María, Av. Santa María 6400, Vitacura, Santiago 7630000, Chile.</nlm:affiliation><country xml:lang="fr">Chili</country><wicri:regionArea>Departamento de Química, Universidad Técnica Federico Santa María, Av. Santa María 6400, Vitacura, Santiago 7630000</wicri:regionArea><wicri:noRegion>Santiago 7630000</wicri:noRegion></affiliation></author><author><name sortKey="Godoy, Patricio" sort="Godoy, Patricio" uniqKey="Godoy P" first="Patricio" last="Godoy">Patricio Godoy</name><affiliation wicri:level="1"><nlm:affiliation>Instituto de Microbiología Clínica, Facultad de Medicina, Universidad Austral de Chile, Los Laureles s/n, Isla Teja, Valdivia 5090000, Chile.</nlm:affiliation><country xml:lang="fr">Chili</country><wicri:regionArea>Instituto de Microbiología Clínica, Facultad de Medicina, Universidad Austral de Chile, Los Laureles s/n, Isla Teja, Valdivia 5090000</wicri:regionArea><wicri:noRegion>Valdivia 5090000</wicri:noRegion></affiliation></author><author><name sortKey="Caro, Nelson" sort="Caro, Nelson" uniqKey="Caro N" first="Nelson" last="Caro">Nelson Caro</name><affiliation wicri:level="1"><nlm:affiliation>Centro de Investigación Australbiotech, Universidad Santo Tomás, Avda. Ejército 146, Santiago 8320000, Chile.</nlm:affiliation><country xml:lang="fr">Chili</country><wicri:regionArea>Centro de Investigación Australbiotech, Universidad Santo Tomás, Avda. Ejército 146, Santiago 8320000</wicri:regionArea><wicri:noRegion>Santiago 8320000</wicri:noRegion></affiliation></author><author><name sortKey="Besoain, Ximena" sort="Besoain, Ximena" uniqKey="Besoain X" first="Ximena" last="Besoain">Ximena Besoain</name><affiliation wicri:level="1"><nlm:affiliation>Escuela de Agronomía Pontificia Universidad Católica de Valparaíso, Quillota, SanFrancisco s/n La Palma, Quillota 2260000, Chile.</nlm:affiliation><country xml:lang="fr">Chili</country><wicri:regionArea>Escuela de Agronomía Pontificia Universidad Católica de Valparaíso, Quillota, SanFrancisco s/n La Palma, Quillota 2260000</wicri:regionArea><wicri:noRegion>Quillota 2260000</wicri:noRegion></affiliation></author><author><name sortKey="Montenegro, Ivan" sort="Montenegro, Ivan" uniqKey="Montenegro I" first="Iván" last="Montenegro">Iván Montenegro</name><affiliation wicri:level="1"><nlm:affiliation>Escuela de Obstetricia y Puericultura, Facultad de Medicina, Universidad de Valparaíso, Angamos 655, Reñaca, Viña del Mar 2520000, Chile.</nlm:affiliation><country xml:lang="fr">Chili</country><wicri:regionArea>Escuela de Obstetricia y Puericultura, Facultad de Medicina, Universidad de Valparaíso, Angamos 655, Reñaca, Viña del Mar 2520000</wicri:regionArea><wicri:noRegion>Viña del Mar 2520000</wicri:noRegion></affiliation></author><author><name sortKey="Madrid, Alejandro" sort="Madrid, Alejandro" uniqKey="Madrid A" first="Alejandro" last="Madrid">Alejandro Madrid</name><affiliation wicri:level="1"><nlm:affiliation>Laboratorio de Productos Naturales y Síntesis Orgánica (LPNSO), Departamento de Química, Facultad de Ciencias Naturales y Exactas, Universidad de Playa Ancha, Avda. Leopoldo Carvallo 270, Playa Ancha, Valparaíso 2340000, Chile.</nlm:affiliation><country xml:lang="fr">Chili</country><wicri:regionArea>Laboratorio de Productos Naturales y Síntesis Orgánica (LPNSO), Departamento de Química, Facultad de Ciencias Naturales y Exactas, Universidad de Playa Ancha, Avda. Leopoldo Carvallo 270, Playa Ancha, Valparaíso 2340000</wicri:regionArea><wicri:noRegion>Valparaíso 2340000</wicri:noRegion></affiliation></author></analytic><series><title level="j">Antibiotics (Basel, Switzerland)</title><idno type="ISSN">2079-6382</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">This work reports on the synthesis of eight new 2'-hydroxy-chalcones with potential anti-phytopathogenic applications in agroindustry, among others, via Claisen-Schmidt condensation and ultrasound assisted reaction. Assays showed three chalcones with allyl moieties strongly inhibited growth of phytopathogenic oomycete <i>Phytophthora infestans</i>; moreover, compound <b>8a</b> had a half maximal effective concentration (EC<sub>50</sub>) value (32.5 µg/mL) similar to that of metalaxyl (28.6 µg/mL). A software-aided quantitative structure-activity relationship (QSAR) analysis of the whole series suggests that the structural features of these new chalcones-namely, the fluoride, hydroxyl, and amine groups over the carbon 3' of the chalcone skeleton-increase anti-oomycete activity.</div></front></TEI><pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">32899705</PMID><DateRevised><Year>2020</Year><Month>10</Month><Day>23</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Print">2079-6382</ISSN><JournalIssue CitedMedium="Print"><Volume>9</Volume><Issue>9</Issue><PubDate><Year>2020</Year><Month>Sep</Month><Day>04</Day></PubDate></JournalIssue><Title>Antibiotics (Basel, Switzerland)</Title><ISOAbbreviation>Antibiotics (Basel)</ISOAbbreviation></Journal><ArticleTitle>Sonochemical Synthesis of 2'-Hydroxy-Chalcone Derivatives with Potential Anti-Oomycete Activity.</ArticleTitle><ELocationID EIdType="pii" ValidYN="Y">E576</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.3390/antibiotics9090576</ELocationID><Abstract><AbstractText>This work reports on the synthesis of eight new 2'-hydroxy-chalcones with potential anti-phytopathogenic applications in agroindustry, among others, via Claisen-Schmidt condensation and ultrasound assisted reaction. Assays showed three chalcones with allyl moieties strongly inhibited growth of phytopathogenic oomycete <i>Phytophthora infestans</i>; moreover, compound <b>8a</b> had a half maximal effective concentration (EC<sub>50</sub>) value (32.5 µg/mL) similar to that of metalaxyl (28.6 µg/mL). A software-aided quantitative structure-activity relationship (QSAR) analysis of the whole series suggests that the structural features of these new chalcones-namely, the fluoride, hydroxyl, and amine groups over the carbon 3' of the chalcone skeleton-increase anti-oomycete activity.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>López</LastName><ForeName>Génesis</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Laboratorio de Productos Naturales y Síntesis Orgánica (LPNSO), Departamento de Química, Facultad de Ciencias Naturales y Exactas, Universidad de Playa Ancha, Avda. Leopoldo Carvallo 270, Playa Ancha, Valparaíso 2340000, Chile.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mellado</LastName><ForeName>Marco</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Instituto de Química, Facultad de Ciencias, Pontificia Universidad Católica de Valparaíso, Av. Universidad #330, Curauma, Valparaíso 2340000, Chile.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Werner</LastName><ForeName>Enrique</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Departamento de Ciencias Básicas, Campus Fernando May Universidad del Biobío. Avda. Andrés Bello 720, Casilla 447, Chillán 3780000, Chile.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Said</LastName><ForeName>Bastián</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Departamento de Química, Universidad Técnica Federico Santa María, Av. Santa María 6400, Vitacura, Santiago 7630000, Chile.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Godoy</LastName><ForeName>Patricio</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Instituto de Microbiología Clínica, Facultad de Medicina, Universidad Austral de Chile, Los Laureles s/n, Isla Teja, Valdivia 5090000, Chile.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Caro</LastName><ForeName>Nelson</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>Centro de Investigación Australbiotech, Universidad Santo Tomás, Avda. Ejército 146, Santiago 8320000, Chile.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Besoain</LastName><ForeName>Ximena</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>Escuela de Agronomía Pontificia Universidad Católica de Valparaíso, Quillota, SanFrancisco s/n La Palma, Quillota 2260000, Chile.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Montenegro</LastName><ForeName>Iván</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Escuela de Obstetricia y Puericultura, Facultad de Medicina, Universidad de Valparaíso, Angamos 655, Reñaca, Viña del Mar 2520000, Chile.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Madrid</LastName><ForeName>Alejandro</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Laboratorio de Productos Naturales y Síntesis Orgánica (LPNSO), Departamento de Química, Facultad de Ciencias Naturales y Exactas, Universidad de Playa Ancha, Avda. Leopoldo Carvallo 270, Playa Ancha, Valparaíso 2340000, Chile.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>1190424</GrantID><Agency>Fondo Nacional de Desarrollo Científico y Tecnológico</Agency><Country></Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>09</Month><Day>04</Day></ArticleDate></Article><MedlineJournalInfo><Country>Switzerland</Country><MedlineTA>Antibiotics (Basel)</MedlineTA><NlmUniqueID>101637404</NlmUniqueID><ISSNLinking>2079-6382</ISSNLinking></MedlineJournalInfo><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Phytophthora infestans</Keyword><Keyword MajorTopicYN="N">chalcone</Keyword><Keyword MajorTopicYN="N">ultrasound</Keyword></KeywordList><CoiStatement>The authors declare no conflicts of interest.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>08</Month><Day>13</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2020</Year><Month>08</Month><Day>28</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>08</Month><Day>31</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>9</Month><Day>9</Day><Hour>1</Hour><Minute>4</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>9</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>9</Month><Day>10</Day><Hour>6</Hour><Minute>1</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32899705</ArticleId><ArticleId IdType="pii">antibiotics9090576</ArticleId><ArticleId IdType="doi">10.3390/antibiotics9090576</ArticleId><ArticleId IdType="pmc">PMC7560025</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Ultrason Sonochem. 2002 Oct;9(5):237-9</Citation><ArticleIdList><ArticleId IdType="pubmed">12371199</ArticleId></ArticleIdList></Reference><Reference><Citation>Bioorg Med Chem. 2007 Sep 1;15(17):5719-37</Citation><ArticleIdList><ArticleId IdType="pubmed">17590342</ArticleId></ArticleIdList></Reference><Reference><Citation>Eur J Med Chem. 2010 Sep;45(9):4258-69</Citation><ArticleIdList><ArticleId IdType="pubmed">20619940</ArticleId></ArticleIdList></Reference><Reference><Citation>Molecules. 2018 Jun 07;23(6):</Citation><ArticleIdList><ArticleId IdType="pubmed">29875340</ArticleId></ArticleIdList></Reference><Reference><Citation>Mol Divers. 2020 Aug;24(3):603-615</Citation><ArticleIdList><ArticleId IdType="pubmed">31161394</ArticleId></ArticleIdList></Reference><Reference><Citation>Bioorg Med Chem. 2006 Mar 15;14(6):1710-4</Citation><ArticleIdList><ArticleId IdType="pubmed">16263298</ArticleId></ArticleIdList></Reference><Reference><Citation>Antibiotics (Basel). 2019 Oct 15;8(4):</Citation><ArticleIdList><ArticleId IdType="pubmed">31618883</ArticleId></ArticleIdList></Reference><Reference><Citation>Bioorg Med Chem Lett. 2010 Feb 1;20(3):942-4</Citation><ArticleIdList><ArticleId IdType="pubmed">20045640</ArticleId></ArticleIdList></Reference><Reference><Citation>Bioorg Med Chem. 2018 Aug 15;26(15):4410-4427</Citation><ArticleIdList><ArticleId IdType="pubmed">30031654</ArticleId></ArticleIdList></Reference><Reference><Citation>J Mol Graph Model. 2002 Jan;20(4):269-76</Citation><ArticleIdList><ArticleId IdType="pubmed">11858635</ArticleId></ArticleIdList></Reference><Reference><Citation>Molecules. 2017 Jun 10;22(6):</Citation><ArticleIdList><ArticleId IdType="pubmed">28604594</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Prod Res. 2012;26(10):892-902</Citation><ArticleIdList><ArticleId IdType="pubmed">21678160</ArticleId></ArticleIdList></Reference><Reference><Citation>Int J Mol Sci. 2016 Aug 22;17(8):</Citation><ArticleIdList><ArticleId IdType="pubmed">27556457</ArticleId></ArticleIdList></Reference><Reference><Citation>Pharm Biol. 2014 May;52(5):655-60</Citation><ArticleIdList><ArticleId IdType="pubmed">24256182</ArticleId></ArticleIdList></Reference><Reference><Citation>Molecules. 2019 Nov 19;24(22):</Citation><ArticleIdList><ArticleId IdType="pubmed">31752322</ArticleId></ArticleIdList></Reference><Reference><Citation>Environ Res. 2019 Feb;169:483-493</Citation><ArticleIdList><ArticleId IdType="pubmed">30530088</ArticleId></ArticleIdList></Reference><Reference><Citation>Molecules. 2012 Aug 29;17(9):10331-43</Citation><ArticleIdList><ArticleId IdType="pubmed">22932214</ArticleId></ArticleIdList></Reference><Reference><Citation>Bioorg Med Chem. 2019 Jan 1;27(1):43-54</Citation><ArticleIdList><ArticleId IdType="pubmed">30482548</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Prod Res. 2015;29(6):586-8</Citation><ArticleIdList><ArticleId IdType="pubmed">25184663</ArticleId></ArticleIdList></Reference><Reference><Citation>J Med Chem. 2013 Jan 10;56(1):31-45</Citation><ArticleIdList><ArticleId IdType="pubmed">23270565</ArticleId></ArticleIdList></Reference><Reference><Citation>Bioorg Med Chem. 2014 Jul 1;22(13):3386-92</Citation><ArticleIdList><ArticleId IdType="pubmed">24835787</ArticleId></ArticleIdList></Reference><Reference><Citation>Future Microbiol. 2020 Jan;15:21-33</Citation><ArticleIdList><ArticleId IdType="pubmed">32043361</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>Chili</li></country></list><tree><country name="Chili"><noRegion><name sortKey="L Pez, Genesis" sort="L Pez, Genesis" uniqKey="L Pez G" first="Génesis" last="L Pez">Génesis L Pez</name></noRegion><name sortKey="Besoain, Ximena" sort="Besoain, Ximena" uniqKey="Besoain X" first="Ximena" last="Besoain">Ximena Besoain</name><name sortKey="Caro, Nelson" sort="Caro, Nelson" uniqKey="Caro N" first="Nelson" last="Caro">Nelson Caro</name><name sortKey="Godoy, Patricio" sort="Godoy, Patricio" uniqKey="Godoy P" first="Patricio" last="Godoy">Patricio Godoy</name><name sortKey="Madrid, Alejandro" sort="Madrid, Alejandro" uniqKey="Madrid A" first="Alejandro" last="Madrid">Alejandro Madrid</name><name sortKey="Mellado, Marco" sort="Mellado, Marco" uniqKey="Mellado M" first="Marco" last="Mellado">Marco Mellado</name><name sortKey="Montenegro, Ivan" sort="Montenegro, Ivan" uniqKey="Montenegro I" first="Iván" last="Montenegro">Iván Montenegro</name><name sortKey="Said, Bastian" sort="Said, Bastian" uniqKey="Said B" first="Bastián" last="Said">Bastián Said</name><name sortKey="Werner, Enrique" sort="Werner, Enrique" uniqKey="Werner E" first="Enrique" last="Werner">Enrique 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